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DISA Med Tech correctly offers a lab-scale
spray coating solution for drug-eluting coronary stents. The companies
drug-delivery technology makes use of an erodible polymeric coating.
This coating together with a suitable drug formulation has been developed
to meet the challenges of combating restenosis. Pre-clinical trials
of coated stents have shown the coating is safe and free of an adverse
inflammatory response. The company can assist in the development of
polymers for the ideal elution profile through optimising the coating
thickness, the drug:polymer ratio, the polymer formulation and other
characteristics. |
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The development of a drug-eluting coronary
stent requires considerable development of the in vitro elution
profile of the drug. DISA Med Tech has development in vitro
methodologies for the drug-elution and also has HPLC equipment and
expertise to determine elution profiles for a variety of drugs.
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